Efficacy and Safety of Bioactive Glass S53P4 as a Treatment for Diabetic Foot Osteomyelitis

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Bioactive glass S53P4 as bone graft substitute in treatment of osteomyelitis.

Bioactive glass (BAG)-S53P4 is an osteoconductive bone substitute with proven antibacterial and bone bonding properties. In a multicentre study 11 patients with verified chronic osteomyelitis in the lower extremity and the spine were treated with BAG-S53P4 as a bone substitute. The cavitary bone defect and the surrounding of a spinal implant were filled with BAG-S53P4. The most common pathogen ...

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Clinical Applications of S53P4 Bioactive Glass in Bone Healing and Osteomyelitic Treatment: A Literature Review

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Treatment of Cavitary Bone Defects in Chronic Osteomyelitis: Biogactive glass S53P4 vs. Calcium Sulphate Antibiotic Beads

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Osteomyelitis and the Diabetic Foot

Diabetic foot infections are associated with significant morbidity, account for the largest number of diabetesrelated hospital bed days and contribute to 50% of all lower extremity amputations in the United States. The annual incidence of foot ulcers in diabetic patients is about 2%, which, given that there are now 15-20 million diabetics nationally, extrapolates to over 300,000 cases per year....

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ژورنال

عنوان ژورنال: The Journal of Foot and Ankle Surgery

سال: 2021

ISSN: 1067-2516

DOI: 10.1053/j.jfas.2020.06.029